Fructosyl-peptide Oxidase (FPOX)
Bayani
Enzyme yana da amfani don ƙayyade fructosyl-peptide da fructosyl-L-amino acid.
Tsarin Sinadarai
Ƙa'idar amsawa
Fructosyl-peptide + H2O + O2→ Peptide + Glucosone + H2O2
Ƙayyadaddun bayanai
Kayan Gwaji | Ƙayyadaddun bayanai |
Bayani | Farin amorphous foda, lyophilized |
Ayyuka | ≥4U/mg |
Tsarki (SDS-SHAFIN) | ≥90% |
Catalase | ≤0.01% |
ATPase | ≤0.005% |
Glucose oxidase | ≤0.03% |
Cholesterol oxidase | ≤0.003% |
Sufuri da ajiya
Sufuri: Na yanayi
Ajiya:Ajiye a -20°C (Logon lokaci), 2-8°C (gajeren lokaci)
An shawarar sake gwadawaRayuwa:shekara 2
Tarihin ci gaba
Ɗaya daga cikin alamun da aka yi amfani da su wajen gano ciwon sukari shine haemoglobin glycated (HbA1c).Auna HbA1c ta amfani da enzymes ya dace don sarrafa adadi mai yawa na samfurori, kuma yana da inganci.Don haka, an daɗe ana kira mai ƙarfi daga likitocin kiwon lafiya don haɓaka irin wannan gwajin enzyme.Saboda haka, mun ƙirƙiri sabon bincike ta amfani da "hanyar dipeptide".Musamman, mun gano "Fructosyl-peptide Oxidase" (FPOX) wanda za'a iya amfani dashi azaman enzyme don wannan binciken.Wannan ya sauƙaƙa nasararmu don cimma nasarar farko ta duniya ta hanyar yin haƙiƙanin gwajin enzyme HbA1c.Wannan "hanyar dipeptide" tana amfani da Protease (Proteolytic enzyme) don rushe HbA1c a cikin jini, sannan auna matakan saccharified dipeptides da aka samar ta amfani da FPOX.Wannan hanyar ta gamu da kyakkyawar liyafar maraba saboda cancantarta na kasancewa mai sauƙi, mara tsada da sauri, kuma HbA1c mai aunawa ta amfani da FPOX yanzu an fara amfani dashi a duk faɗin duniya.