Doxycycline Hyclate (24390-14-5)
Bayanin Samfura
● Doxycycline Hcl ne antibacterial bakan yana kusa da Tetracycline da Terramycin, amma yana da sakamako mafi kyau, kula da Staphylococcus Aureus na tetracycline-resistant, oxytetracycline, tsawon lokaci mai tsawo. Ana amfani dashi sau da yawa a cikin tsofaffi na kullum Bronchitis, cututtuka na numfashi na numfashi, huhu kamuwa da cuta, m tonsillitis, mycoplasma ciwon huhu, urinary fili kamuwa da cuta, jini guba, bacillary dysentery, m lymphadenitis, da dai sauransu Yana da matukar farin jini ga majiyyacin Nephropathy saboda rashin bayyana guba ga koda.
Doxycycline Hyclate shine nau'in gishiri mai hyclate na doxycycline, roba, maganin rigakafi na tetracycline mai fadi da ke nuna aikin rigakafin ƙwayoyin cuta.Doxycycline hyclate yana ɗaure ta sake komawa zuwa sashin ribosomal na 30S, maiyuwa zuwa 50S ribosomal subunit kuma, ta haka yana toshe ɗaurin aminoacyl-tRNA zuwa hadaddun mRNA-ribosome.Wannan yana haifar da hana haɗin furotin.Bugu da ƙari, wannan wakili ya nuna hana ayyukan collagenase.
Aikace-aikace
Ana amfani da Doxycycline Hyclate don magance cututtukan ƙwayoyin cuta iri-iri, gami da waɗanda ke haifar da kuraje.Ana kuma amfani da Doxycycline Hyclate don hana zazzabin cizon sauro.Doxycycline Hyclate an san shi azaman rigakafin tetracycline.Yana aiki ta hanyar dakatar da haɓakar ƙwayoyin cuta.Wannan maganin rigakafi yana magance cututtukan ƙwayoyin cuta kawai.
| Abubuwa | Ƙayyadaddun bayanai | Sakamako |
| Bayyanar | Yellow crystalline foda | Ya dace |
| Ganewa | TLC | Ya dace |
| sulfuric acid dauki wani rawaya launi tasowa | Ya dace | |
| yana ba da amsawar chlorides | Ya dace | |
| PH | 2.0 ~ 3.0 | 2.3 |
| Musamman sha | a 349nm e (1%) 300 ~ 355 | 320 |
| Takamaiman jujjuyawar gani | -105 ~ -120 ° | -110° |
| Karfe masu nauyi: | ≤50ppm | <20pm |
| Najasa masu ɗaukar haske | da 490nm ≤0.07 | 0.03 |
| Abubuwan da ke da alaƙa | 6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) Oxytetracycline ≤0.5% (ep5) wani rashin tsarki ≤0.5% Ba a gano ƙazanta ba ≤0.1% (ep5) | 1.6% 0.1% Ba a samu ba Ba a samu ba Ba a samu ba Ba a samu ba Ba a samu ba |
| Ethanol | 4.3 ~ 6.0% (m/m) | 4.5% |
| Sulfate ash | ≤0.4% | 0.05% |
| Ruwa | 1.4 ~ 2.8% | 1.8% |
| Assay | 95.0 ~ 102.0% (c22h25cln2o8) dangane da anhydrous, abun da ba shi da ethanol | 98.6% |
| Kammalawa | Yi daidai da USP32 | |
